M2i2 2014 Collaborations and Studies

Merck Medical Information and Innovation
Building an ecosystem of strategic collaborations to enhance health IT
and data-driven capabilities for our collaborators and Merck so we can
work together to advance science, improve public health and clinical
care, and support patient engagement.

2014

Collaborations
and Studies
It’s a banner year for
innovative collaborations
with organizations that
have unlocked mutual value
across the ecosystem.

C O L L A B O R ATO R S

KEY AREAS
Personalized
Delivery
of Care

HPV

Osteoporosis

Comparative
Effectiveness

Clinical
Decision
Support

EMR

Alzheimer's

Health IT

Diabetes

Adherence

Disease Areas

Population
Health

Cardiovascular

Oncology

Hepatitis C

Content Areas

Global
Data Access

Patient Voice

Insomnia

Patient
Engagement

C O L L A B O R AT I O N S A N D S T U D I E S
M2i2’s global strategic collaborations focus on: health information technology / digital health and access
to data and external analysis. They leverage Merck’s scale and expertise to enhance data-driven approaches, improve
population health and clinical care, and support patient engagement while giving Merck access to leading-edge talent,
innovation and opportunities in the context of marketplace changes driven by the Affordable Care and HITECH Acts.

Northwestern

Maccabi

StartX

M2i2 is collaborating with Northwestern
University, Alliance of Chicago, and Walgreens
on a landmark health IT interventional study
evaluating the impact of providing simplified
and clear medication instructions. Currently,
physician practices and pharmacies use
different electronic record systems for writing
prescriptions and translating them onto the
medicine label.

Maccabi Healthcare, one of Israel’s largest
health systems, has over 20 years of clinical
and claims data history. Maccabi and Merck
will apply technical and information research
capabilities to draw insights from Maccabi’s
data to support personalized health care
delivery strategies across several therapeutic
areas, including prevalent and costly
chronic diseases.

Merck joined StartX, a Stanford University
non-profit spinoff in the heart of Silicon Valley,
as a corporate partner to provide strategic
guidance to promising health technology
entrepreneurs to build innovative healthcare
solutions. As a corporate partner, Merck will
have access to disruptive innovations in data,
analytics and digital health as well as exposure
to world class talent and ideas.

Regenstrief Institute

Humedica (Optum)

Merck’s multi-year partnership with the
Regenstrief Institute is a novel collaboration
between a pharmaceutical company and a
health information exchange. The scale of
the Institute’s data assets (approximately 13M
unique patients) combined with their
informatics capabilities will allow Merck to
advance our insights in osteoporosis, HPV,
diabetes and oncology.

Researchers across Merck are utilizing
Humedica's clinical intelligence platform
to derive real world insights. Moving beyond
claims-based analysis, the Humedica asset
captures lab results, vital signs and includes
unique natural language processed data
that supports Merck’s observational research
efforts in real-world settings.

CBMI at Harvard
Medical School

Health Data Consortium

PatientsLikeMe

(Merck | HPN ACO Challenge)
HDC brings together organizations from
government, non-profit and the private sector
to advocate for open, intelligent use of data to
improve health. As part of the Consortium,
Merck and Heritage Provider Network, an ACO,
are hosting an innovation challenge – the first
pharma/ACO collaboration of its kind – to find
solutions that improve care plan adherence.

PatientsLikeMe, a patient network with over
250,000 members, helps increase
understanding of the real-world disease
burden of a variety of conditions. The
community facet of PLM’s platform unlocks
insight into patient perspectives that helps
patients learn from each other and will help
Merck's researchers better understand patients
and develop more effective solutions.

The Center for Biomedical Informatics created
the Informatics for Integrating Biology & the
Bedside (i2b2) platform, adopted by over 100
academic health centers in linking their EMR
systems with biobank and genomic information.
CBMI’s expertise in digital libraries enables
Merck to co-develop methodology to analyze
the pathophysiology and underlying
mechanisms of insomnia and physician
prescribing behavior.

Boston Children’s
Hospital | Harvard
M2i2 is working with the premier computational
epidemiology lab in the US on an unique study
analyzing data from Twitter to create digital
definitions for insomnia. This research also aims
to contribute new and meaningful information
to the scientific community on the predictors
of sleep deprivation based on social
media-related behaviors.

Practice Fusion

CECity

Huaxi Hospital

M2i2 is accelerating care delivery innovation
by partnering with Practice Fusion, a cloudbased EMR provider engaged in point-of-care
CDS and population health management.
Merck and Practice Fusion are co-developing
communications to roll into the CDS and the
EMR intelligence platform to help improve
quality of care.

CECity, a cloud-based technology company,
is collaborating with the National Bone Health
Alliance, NOF and three academic medical
centers in a demonstration study to assess the
potential to improve quality of care in patients
with osteoporosis. CECity will use their platform
to study the ability to scale quality improvement and coordinate care to address care gaps
and drive improvement for post-fracture
patients.

M2i2 is supporting a novel research
collaboration with West China Hospital of
Sichuan University (Huaxi Hospital), the
largest single-site hospital in the world and
a leading medical center of West China, to
explore the impact of diabetes on mortality
in non-ICU inpatients.

Allscripts

Smart Patients

M2i2 is accelerating care delivery innovation
by partnering with Allscripts, a healthcare
IT focused company and EMR provider.
Merck and Allscripts are co-developing CDS
content based on industry guidelines
that would be accessible through the EMR
at the point-of-care.

Smart Patients is an online community where
cancer patients and caregivers learn from each
other about treatments, clinical trials and the
latest scientific breakthroughs. Merck is
leveraging real-world insights from the Smart
Patients network to better understand patient,
clinician and caregiver voices and perspectives.

Data & Analytics
Health Information Technology
/ Digital Health

T H A N K YO U !
We would like to thank our colleagues within and outside of Merck. The M2i2 community is extremely fortunate
to welcome a premier class of health IT and data organizations with a shared vision for improving health. And we are
lucky to have world-class informatics and research colleagues working with our collaborators around the world to
drive value for patients.

TEAM

Merck Medical Information and Innovation
Our senior staff represents diverse perspectives from the top ranks of government,
clinical medicine, and industry.

Dr. Sachin Jain
Chief Medical Information and Innovation Officer (CMIO)
Additionally: Lecturer in Health
Care Policy and Medicine,
Harvard Medical School;
attending physician, Department
of Veterans Affairs

Previously: Senior Advisor to the
Administrator of CMS, where he
helped lead implementation of the
Affordable Care Act and the
launch of the Center for Medicare
and Medicaid Innovation

Dr. Tom Tsang

Paulien Meijer

Dr. Aman Bhandari

Executive Director

Executive Director

Director

Previously: Staff member in the
House of Representatives, where
he authored critical portions of the
Affordable Care Act and assisted
in Centers for Medicare and
Medicaid Innovation

Previously: Long-time leader in
Merck's Global Market Access
Organization

Previously: Held positions at the
White House, Centers for Medicare
and Medicaid Services, Genentech
and the VA

Chris Yu

Bryan Mallitz

Arnaub Chatterjee

Director

Director

Associate Director

Previously: SVP, U.S. Healthcare,
Voxiva, a leading mobile health
patient engagement company

Previously: Leadership positions
in health IT strategy and
development at Merck

Previously: Special Assistant to
the CTO of US Department of
Health and Human Services and
former management consultant
at Deloitte

For questions please email Aman Bhandari or Sachin Jain: m2i2@merck.com
Today's Merck is a global healthcare leader working to help the world be well. Merck is known as MSD outside the United States and
Canada. Through our prescription medicines, vaccines, biologic therapies, and consumer care and animal health products, we work with
customers and operate in more than 140 countries to deliver innovative health solutions. We also demonstrate our commitment to
increasing access to healthcare through far-reaching policies, programs and partnerships.

For more information, visit www.merck.com and connect with us on Twitter, Facebook and YouTube.

M2i2 2014 Collaborations and Studies

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